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filingDate 2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106727422-B
titleOfInvention A kind of polydioxanone is the core-shell structure copolymer bilayer microballoon and its preparation method and application of core
abstract The present invention relates to the nucleocapsid bilayer microballoons and its preparation method and application that a kind of polydioxanone is core, belong to biomedicine technical field, the present invention provides the nucleocapsid bilayer microballoons and preparation method thereof that a kind of polydioxanone is core, this method includes mainly the preparation of polydioxanone microballoon and prepares the double-deck microballoon with nucleocapsid by core of the microballoon, this method is easy to operate, reproducible, at low cost, and preparation process is environmentally friendly.Microspherulite diameter size obtained is close, controllable, and safety is degradable, and histocompatbility is good, and it is slow to degrade, and degradation time can be regulated and controled according to the type and core-shell material adding proportion of shell material.The microballoon can be widely used for sustained release or the fields such as controlled release drug and bioactive substance, cosmetics, soft tissue augmentation and reparation.
priorityDate 2017-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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