http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106699690-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-15 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2016-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106699690-B |
| titleOfInvention | A kind of pleuromutilin derivative and its preparation method and application with acyl piperazine base side chain |
| abstract | The invention belongs to field of medicinal chemistry, disclose a kind of pleuromulins compound and its preparation method and application with acyl piperazine base side chain.The pleuromutilin derivative is compound and its officinal salt with the structure as shown in formula 3, formula 4 and formula 5.Wherein, R 1 、R 2 、R 3 It is each independently selected from one of the alkoxy that hydrogen atom, hydroxyl, amino, sulfydryl, methylol, amine methyl, nitro, halogen, trihalomethyl group, methyl, natural amino acid acylamino- and carbon atom number are 1~6.The present invention has good inhibition staphylococcus aureus and mycoplasma activity with the pleuromulins compound of acyl piperazine base side chain, particularly suitable as novel antibacterial drug for preventing and treating infectious diseases caused by human or animal infects through mycoplasma or Multidrug resistant bacteria. |
| priorityDate | 2016-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.