http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106691888-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-413 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-591 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-342 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-498 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-86 |
filingDate | 2015-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106691888-B |
titleOfInvention | Glabridin nano composition with high skin retention and preparation method and application thereof |
abstract | The invention relates to a glabridin nano composition with high skin retention, a preparation method and application thereof, wherein the glabridin nano composition comprises, by mass, 0.1% -6.0% of glabridin, 2.0% -10.0% of solid lipid, 1.0% -6.0% of liquid lipid, 0.5% -5.0% of octyldodecanol, 0.5% -5.0% of vitamin E polyethylene glycol succinate, 5.0% -20.0% of polyalcohol and the balance of purified water, an oil phase prepared from the glabridin, the solid lipid, the liquid lipid and the octyldodecanol is dripped into a water phase prepared from the vitamin E polyethylene glycol succinate, the polyalcohol and the purified water, and the oil phase is treated by high-speed shearing emulsification, high-pressure homogenization or high-pressure micro-jet equipment. The glabridin nano composition has large drug-loading rate, can promote the glabridin to penetrate through the skin and stay at high concentration for a long time, has good stability and high safety, has a simple and easily-controlled preparation method, and is suitable for industrial production. |
priorityDate | 2015-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 94.