| abstract |
The present invention discloses indazole compounds of formula (I) as cyclin-dependent kinases (CDKs) and cell proliferation inhibitors, and their medical uses and preparation methods. Such compounds and their pharmaceutically acceptable salts, solvates, prodrugs and pharmaceutical compositions are useful in the treatment of diseases and disorders related to the activity of cyclin-dependent kinases, especially CDK4/6, which diseases and disorders include, but are not limited to, diseases or conditions associated with various cancers and inflammations. (I). |