http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106674425-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-1804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F222-102 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F220-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F2-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F222-1006 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F2-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-28 |
| filingDate | 2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106674425-B |
| titleOfInvention | A kind of preparation method of the nanosphere of pH response Vancomycin |
| abstract | The invention discloses a kind of preparation methods of the nanosphere of pH response Vancomycin, it stirs evenly the dissolution of template molecule vancomycin, function monomer hydroxyethyl methacrylate and diethyl aminoethyl methacrylate to obtain mixed liquor in deionized water, then crosslinking agent and photoinitiator dissolution are dropped to afterwards in ethanol in the mixed liquor under stirring, reaction mixture is obtained after stirring；Reaction mixture pours into three-necked flask and is placed on 1-3h at 4 DEG C, nitrogen is passed through into flask again the air in flask is discharged, the flask is placed at 15-35 DEG C and receives to obtain the nanosphere for being loaded with vancomycin after wavelength stirs 0.5-1.5h for the ultraviolet light and continued mechanical of 365nm.Of the present invention preparation method is simple, and consumption resource is few, and the method using the precipitation polymerization of ultraviolet initiation is economic and environment-friendly, vancomycin will not be made to thermally decompose at high temperature, and nanosphere drugloading rate obtained is high, can effectively control the release of vancomycin. |
| priorityDate | 2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.