http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106674213-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8dbfd4a8f52e70de64bb56a0dabe1ce |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 |
| filingDate | 2015-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0266fe87f90abf8f9829d4090af09a7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c6e8bbccce3d6def16da9baf46c59fb |
| publicationDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106674213-A |
| titleOfInvention | Preparation method of furilazole |
| abstract | The invention relates to a preparation method of furilazole. The method comprises the following steps: dropwisely adding furfural into a container filled with cyanotrimethylsilane and a catalyst, and uniformly stirring and mixing the solution; dropwisely adding the mixed solution into a non-protonic solvent containing lithium aluminum hydride; cooling the solution to room temperature, adding a sodium hydroxide solution to carry out neutralization reaction, and after the reaction finishes, carrying out filtration, drying and distillation to obtain a solid; adding an acetone/toluene sulfonic acid benzene solution into the solid, and stirring to carry out reflux reaction; finally adding sodium hydroxide and dichloroacetyl chloride into the solution, and stirring to react at -10-0 DEG C; and after the reaction finishes, pumping the solution into ice water, standing to stratify, and removing the water layer and oil layer, thereby finally obtaining the furilazole. The method has the advantages of reasonable preparation raw material selection and low cost. In the preparation process, the reflux reaction is firstly carried out at high temperature, and then standing and layering are carried out in a low-temperature place, thereby obtaining the furilazole. Thus, the method is convenient for preparation and high in efficiency. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110041294-A |
| priorityDate | 2015-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.