http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106674182-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-36 |
| filingDate | 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106674182-B |
| titleOfInvention | Formoononetin derivative, preparation method containing dithiocarbamates and its application in antitumor drug |
| abstract | The formoononetin derivative that the invention discloses one kind containing dithiocarbamates, their preparation method and its application in antitumor drug, belong to medicinal chemistry art.The present invention is combined formoononetin parent nucleus with dithiocarbamates activity unit, is simple and efficient the formoononetin derivative synthesized environmentally protectively containing dithiocarbamates.It has the following structure general formulaļ¼ Such Compound ira vitro active anticancer to kinds of tumor cells EC 109, MGC 803, PC 3 experiments have shown that all have certain inhibiting effect.Compared to natural formoononetin, the anti-prostate cancer activity of the formoononetin derivative I 8 containing dithiocarbamates about improves 28 times, can be used as the candidate further developed or lead compound, applied to preparing antitumor drug. |
| priorityDate | 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.