http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106674171-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88 |
| filingDate | 2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106674171-B |
| titleOfInvention | A kind of preparation method of 3- trifluoromethyls phthalide |
| abstract | The invention discloses a kind of preparation method of 3- trifluoromethyls phthalide, step is：Organic solvent is added after mixing in proportion in 2- formylbenzoates ester, trifluoromethyl trimethylsilane and potassium carbonate, is stirred to react, after reaction; it is extracted with ethyl acetate and water, isolated organic phase, it is dry; vacuum distillation removes solvent, and product 3- trifluoromethyl phthalides are obtained through column chromatography.The present invention selects 2- formylbenzoates ester cheap and easy to get as raw material, and reactivity is high, and reaction condition is mild; without adding transition metal salt as catalyst, environmental hazard is reduced, is reacted using one pot of two-step method; product yield high, by-product is few, is suitable for industrialized production. |
| priorityDate | 2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.