http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106674116-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ce58d6b1dbe1bc3bfad551a58ccb034 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-38 |
| filingDate | 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04387f20d48b4ec5b7a519dd185ea3e2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d0df16cb2762a270857f16063714530 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d26892c3ce8c1aa3b43d9f3bee8704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38bbac7cb9bd6450a5651d809da47d2f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe641151cdb9ca2c3edb68baa5e85e59 |
| publicationDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106674116-A |
| titleOfInvention | Synthetic method of 4-amino-1,3-dimethylpyrazole and pharmaceutically acceptable salt thereof |
| abstract | The invention discloses a synthesis method of 4-amino-1,3-dimethylpyrazole and a pharmaceutically acceptable salt thereof. The method starts with methylhydrazine and 4,4-dimethoxy-2-butanone Raw materials, first synthesize 1,3-dimethylpyrazole, then add concentrated nitric acid for nitration to obtain 4-nitro-1,3-dimethylpyrazole, and then directly reduce it to a pharmaceutically acceptable salt, or first nitrate the nitro-1,3-dimethylpyrazole After reduction to the amino group, it is converted to 4-amino-1,3-dimethylpyrazole. The raw materials used in the synthesis method of the invention are low in price, low in cost and easy to obtain. Moreover, the present invention has short synthetic route, high yield, high chemical purity of the obtained product, all reactions do not need special production equipment, and the obtained intermediate and final product do not need column chromatography and crystallization purification. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112574095-A |
| priorityDate | 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.