| abstract |
The present invention describes compositions and methods for preparing media, feeds and supplements. Such methods and media can exhibit increased stability of labile components and can use, for example, microsuspension and/or encapsulation techniques, chelation, and optionally, coating with antioxidants and/or Or mixed with unstable compounds. The composition can tolerate heat and/or radiation treatment with reduced virus numbers. These techniques can produce products with extended shelf-life, extended release of their internal components into culture, or can use minimal volumes to produce products that can be aseptically added to bioreactors. The compositions and methods can optimize biological production workflows and increase efficiency. |