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filingDate 2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106632949-B
titleOfInvention The polyurethane fiber dressing and preparation method of a kind of chitosan oligosaccharide or derivatives thereof modification
abstract The invention belongs to biomedical material technology, the polyurethane fiber dressing and preparation method of a kind of chitosan oligosaccharide or derivatives thereof modification are disclosed.Preparation method of the present invention is the following steps are included: cause the ring-opening polymerisation of alkynyl lactide monomers, synthesis biodegradable polyesters ether of the side chain containing alkynyl using polyethylene glycol;Using it as soft segment, Biodegradable polyurethane of the side chain containing alkynyl is synthesized with diisocyanate and chain extender reaction;Synthesize Azide chitosan oligosaccharide or derivatives thereof;Biodegradable polyurethane of the side chain containing alkynyl is reacted with Azide chitosan oligosaccharide or derivatives thereof generation click chemistry, the polyurethane of synthesis chitosan oligosaccharide or derivatives thereof modification;The polyurethane fiber dressing of chitosan oligosaccharide or derivatives thereof modification is constructed by electrostatic spinning technique.The polyurethane fiber dressing that the method for the present invention obtains has good flexibility, tension stress, water suction and gas permeability, the biological function of suitable porous structure and control bacterium infection and promotion wound repair, it is expected to be widely applied.
priorityDate 2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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