http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632686-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y104-03002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0022 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106632686-B |
| titleOfInvention | anti-IL-4R single-chain antibody and snake venom L-amino acid oxidase fusion protein and application thereof |
| abstract | The invention discloses a fusion protein of anti-IL-4R single-chain antibody and snake venom L-amino acid oxidase, which is prepared by the following steps: connecting the anti-IL-4R single-chain antibody and the trimeresurus venulosus LAAO gene into a scFv-LAAO fusion gene by an overlap extension PCR technical method, constructing a recombinant plasmid pET28a-scFv-LAAO, transferring into BL21(DE3) prokaryotic expression bacteria, and performing induced expression on the scFv-LAAO fusion protein to obtain the recombinant scFv-LAAO fusion protein. The invention adopts an expression vector of a fusion gene of an anti-IL-4R single-chain antibody gene (scFv) and snake venom L-amino acid oxidase by adopting a molecular biology technology to perform in vitro expression, and recombines the fusion protein of the anti-IL-4R single-chain antibody and the snake venom L-amino acid oxidase, wherein the fusion protein of the anti-IL-4R single-chain antibody and the snake venom L-amino acid oxidase can be used for treating lung cancer, and has good curative effect and no side effect basically. |
| priorityDate | 2016-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 222.