http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632655-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-57563 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 |
filingDate | 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106632655-B |
titleOfInvention | Preparation method of exenatide and product thereof |
abstract | The invention discloses a preparation method of exenatide, which comprises the steps of Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-CONH 2 The full-protection fragment of (a) is prepared from the following full-protection fragments of three fragments: Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-COOH, Thr-Ser-Asp-Leu-Ser-Lys-Gln-COOH, His-Gly-Glu-Gly-Thr-Phe-COOH. The invention overcomes the problems of difficult purification and difficult scale of the existing solid-phase synthesis exenatide, improves the synthesis efficiency, reduces the accumulation of impurities and reduces the purification difficulty. |
priorityDate | 2016-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 151.