http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632416-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate | 2016-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106632416-B |
titleOfInvention | Using 1- (2- pyridines) -9- isopentyl-B-carboline as the chlorination copper complex and its synthetic method of ligand and application |
abstract | The invention discloses one kind using 1 (2 pyridine) 9 isopentyl β carbolines as the chlorination copper complex and its synthetic method of ligand and application.Shown in the structural formula of the complex such as following formula (I), synthetic method is:Take compound and copper chloride as shown in following formula (II), be dissolved in polar solvent, carry out complexation reaction to get;Wherein, the polar solvent be selected from one or both of methanol and ethyl alcohol with selected from water, acetone, chloroform, dichloromethane and N, the combination of one or more of N dimethylformamides.Complex of the present invention shows antitumor activity more stronger than ligand and cis-platinum, has preferable potential medical value, is expected to be used for the preparation of various antitumor drugs.Structure is as follows shown in formula (I) and formula (II): |
priorityDate | 2016-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 104.