http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632339-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106632339-B |
| titleOfInvention | A kind of 6- substitution -9H- purine analog derivative and its preparation method and application |
| abstract | The invention discloses a kind of 6- substitution -9H- purine analog derivatives and its preparation method and application; shown in structure such as formula (I); R is selected from one kind of pyrrolidinyl, furans -2- methyl, benzenesulfonyl, substitution or unsubstituted phenyl or benzyl; wherein, the substituent group on phenyl or benzyl is independently selected from C 1 ~C 4 Alkoxy, C 1 ~C 4 Alkyl, hydroxyl, halogen, One or more of；R 4 Independently selected from H or alkyl-substituted benzyl.Test result shows, compared with gold ion (inhibitor 3) is complexed in 6- benzyl purine compound, 6- substitution -9H- purine analog derivative of the invention is higher to the inhibiting rate of inflammatory factor, has better anti-inflammatory activity, has the potentiality as anti-inflammatory drug. |
| priorityDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.