http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632338-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106632338-B |
| titleOfInvention | A kind of 9- substitution-N-（2- chlorobenzyl）Purine -6- amine derivant and its preparation method and application |
| abstract | The invention discloses a kind of 9- substitution-N-（2- chlorobenzyl）Purine -6- amine derivant, shown in structure such as formula (I), R is selected from hydrogen atom, C 1 ~C 4 One of alkyl, substitution or unsubstituted benzyl, wherein the substituent group on benzyl is independently selected from halogen ,-CF 3 、C 1 ~C 4 Alkoxy, C 1 ~C 4 One or more in alkyl and nitro；R 4 To replace or unsubstituted phenyl or benzyl, wherein the substituent group on phenyl or benzyl is one or more in halogen or methoxyl group.Test result shows, compared with gold ion (inhibitor 3) is complexed in 6- benzyl purine compound, 9- substitution-N- (2- chlorobenzyl) purine -6- amine derivative of the invention is higher to the inhibiting rate of inflammatory factor, with better anti-inflammatory activity, there are the potentiality as anti-inflammatory drug. |
| priorityDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 147.