http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632041-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D221-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-28 |
filingDate | 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106632041-B |
titleOfInvention | A kind of preparation method of Levallorphane Tartrate |
abstract | The present invention provides a kind of preparation methods of Levallorphane Tartrate, belong to drug and chemosynthesis technical field.This method is using homoanisic acid and 2-(cyclohexenyl group) ethamine as starting material through acylated condensation, the hydrolysis of Bischler-Napieralski annulation, imine reduction, ehter bond, split, N- alkylation, Grewe cyclization and at salt totally nine steps reaction.The method obtains Levallorphane Tartrate and each intermediate with high yield, high-purity, can be used as industrial method and is mass produced. |
priorityDate | 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.