http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106632000-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4418 |
filingDate | 2016-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106632000-B |
titleOfInvention | Diaryl ketone compound application in preparation of anti-tumor drugs |
abstract | The present invention relates to field of antineoplastic medicaments.Provide diaryl first ketone compounds application in preparation of anti-tumor drugs.The diaryl first ketone compounds are formula M11, M13, M14, M15, M-126, M128, M130, M131, M132, M149 compound represented.It is tested by antitumor activity, these compounds all show that the activity of a degree of anti-tumour cell proliferative, most compounds show very strong depression effect;Can potent inhibition growth of tumour cell, apoptosis can be inspired in very low concentrations, show stronger inhibitory effect relative to positive reference compound.The preparation process of such compound is simple and easy, and low in raw material price is easily obtained;It can seek its antitumor action target spot by structure activity study, provide valuable guiding role for further drug development.Diaryl first ketone compounds of the present invention provide the foundation for new medicament screen. |
priorityDate | 2016-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.