http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106631792-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-31 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-734 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-732 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-327 |
| filingDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106631792-B |
| titleOfInvention | A kind of synthetic method of-ten hexacarboxylic acid ester of 16- hydroxyl -9- alkene |
| abstract | The invention belongs to field of medicine and chemical technology, specially a kind of synthetic method of-ten hexacarboxylic acid ester of 16- hydroxyl -9- alkene.Method includes the following steps: 1), using polyhydrony fatty acid as reaction starting material; it is then added into stand up reaction bottle, and silicone oil and ortho acid contracting acid esters is added, under nitrogen protection; controlling synthesis reaction temperature is 50 ~ 120 DEG C, and the reaction time is 2 ~ 8h；2) Olefination catalysts, are continuously added, controlling Olefination reaction temperature is 110 ~ 180 DEG C, and the reaction time is 3 ~ 8h；3) it, is cooled to room temperature, appropriate H is added 2 Then O, stirring hydrolysis about 30min adjust pH to 5.0, ethyl acetate extraction, anhydrous sodium sulfate is dry, and rotation is evaporated to obtain-ten hexacarboxylic acid ester of crude product 16- hydroxyl -9- alkene.This method is easy to operate, and the involved reagent of reaction is environmentally friendly, and target product isolates and purifies simply. |
| priorityDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.