http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106608913-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-505 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-505 |
| filingDate | 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106608913-B |
| titleOfInvention | 1, 2, 3-propanetriacid coupled EPO (erythropoietin) peptidomimetic derivative and preparation method and application thereof |
| abstract | 1, 2, 3-propanetriacid coupled EPO peptide-like derivative and its preparation method and application. The invention relates to a 1, 2, 3-tricarballylic acid coupled erythropoietin peptide mimic derivative and a dimer thereof, wherein the peptide mimic derivative is a monomer peptide with a sequence shown as SEQ ID NO. 1: 1GGLYAC6HMGPITX SEQ ID NO 1 VC15QP LRX 2 K; wherein, X 1 Is 3- (1-naphthyl) -L-alanine (Nal), X 2 The general formula of the dimer is shown in the formula I, and the invention also provides a preparation method of the peptide mimetic derivative and the dimer and a medicinal salt thereof. The invention further provides a pharmaceutical composition containing the above peptidomimetics derivative or dimer or a pharmaceutically acceptable salt thereof. The erythropoietin peptidomimetic derivatives, the dimers and the pharmaceutically acceptable salts thereof can stimulate erythropoiesis and obviously prolong the half-life of the medicament in vivo. |
| priorityDate | 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.