http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106608788-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2523-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2531-025 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C245-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C245-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C13-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C245-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C245-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C2-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-263 |
| filingDate | 2016-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106608788-B |
| titleOfInvention | A kind of preparation method of mild diazomethane derivative |
| abstract | The invention discloses a kind of preparation method of mild diazomethane derivative, the preparation method of the diazomethane derivative includes the following steps: the benzene sulfonyl chloride for replacing EWG and hydration hydrazine reaction, obtains the benzene sulfonyl hydrazide of EWG substitution；Benzene sulfonyl hydrazide that EWG replaces is reacted to obtain the benzene sulfonyl hydrazone that EWG replaces with aldehydes or ketones；Metathesis reaction is carried out after the benzene sulfonyl hydrazone that EWG replaces is mixed with alkali and organic solvent and obtains diazomethane derivative, which purifies without isolation, is further used for the synthetic reaction and intercalation reaction of the small ring of tension.The present invention introduces drawing electron group EWG on the phenyl ring of benzene sulfonyl hydrazone, using electronic effect and space steric effect, so that the benzenesulfonyl on benzene sulfonyl hydrazone is more easier to leave away, to especially generate diazomethane derivative at room temperature as mild as a dove. |
| priorityDate | 2016-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 126.