http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106596967-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6848 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2016-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106596967-B |
| titleOfInvention | A kind of quantitative approach of stable isotope phosphorylated labelled protein |
| abstract | A kind of quantitative approach of stable isotope phosphorylated labelled protein, is related to Protein quantitative analysis.Using the commercially available small molecule containing labels such as carbon 13, oxygen 18 or deuteriums 2 as raw material, pass through hydrolysis of the halogenated hydrocarbons under silver salt promotion, the alcohol of the isotope labellings such as carbon containing 13 and oxygen 18 is selectively synthesized, then the phosphite ester labelled reagent of the stable isotope labelings such as carbon containing 13, oxygen 18 or deuterium 2 is obtained by the reaction by base exchange.By combining different stable isotope labeling phosphite esters, more flux albumen relative quantitative assay such as two marks, three marks, four marks or five marks are obtained, the molecular weight difference between each label is greater than or equal to 3 dalton.Stable isotope N phosphorylateds labelled protein quantitatively has preferable accuracy, high sensitivity, the interference of No Parity element effect and wide applicability. |
| priorityDate | 2016-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 331.