http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106591313-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-16 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57449 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1048 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106591313-B |
titleOfInvention | The aptamer WYZ-1 and its screening technique of ovarian mucinous cancer cell 3AO and application |
abstract | The present invention relates to the aptamer WYZ-1 of ovarian mucinous cancer cell 3AO a kind of and its screening technique and applications, the sequence of the aptamer WYZ-1 are as follows: 5 '-AGCTGCTATACTAGCTAAAGCCTTAGCTAGCTCAATAACGCGATATAGCATGCGCG ATGCCCGTAGCGATAGCTAGCTT-3 ', its screening technique are as follows: be based on SELEX screening technique, using ovarian serous cancer cell SKOV3 and normal ovarian epithelial cell IOSE as counter-selection cell, it is positive sieve cell with ovarian mucinous cancer cell 3AO, filter out the aptamer with ovarian mucinous cancer cell 3AO specific binding, it has high specific, high-affinity, it can body Outer synthesis and modification, the features such as chemical property is stable, pharmacokinetic property is good, non-immunogenicity. |
priorityDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.