http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106589290-B

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classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2230-00
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-428
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filingDate 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106589290-B
titleOfInvention A kind of high-biocompatibility Phosphorylcholine modified polyurethane material and preparation method thereof
abstract The present invention relates to a kind of high-biocompatibility Phosphorylcholine modified polyurethane materials and preparation method thereof, preparation method the following steps are included: (1) both-end isocyanate group prepolymer preparation: both-end Hydroxyl Prepolymers are mixed with excessive diisocyanate, reaction, obtains both-end isocyanate group prepolymer;(2) preparation of Phosphorylcholine modified polyurethane: after the Phosphorylcholine compound of double amino is dissolved in solvent, being added drop-wise in both-end isocyanate group prepolymer, carries out chain extending reaction to both-end isocyanate-based prepolymers and obtains Phosphorylcholine modified polyurethane material.Film prepared by the material has good mechanical performance, produces hydrophilic interface in aqueous solution in the Phosphorylcholine group of side chain, has very low adsorbance to protein in blood, while the material has biodegradable.The material can be used as organizational project renovating bracket material etc. and be applied to organism for a long time, and the catabolite in later period can be absorbed by organism.
priorityDate 2016-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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