http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106589043-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J63-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 |
filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106589043-B |
titleOfInvention | Aryl substituted acryl triterpene compound is preparing the purposes in anticomplement medicament |
abstract | The invention belongs to field of traditional Chinese medicine pharmacy, it is related to aryl substituted acryl triterpene compound in scaly holly root and is preparing the new application in anticomplement medicament.The present invention extracts 5 aryl substituted acryl triterpene compounds using activity guiding separation method from the root of Aquifoliaceae (Aquifoliaceae) plant Flos Ilicis Asprellae (Ilex asprella); through carrying out including that classical pathway and alternative pathway anti-complement activity are evaluated to compound; the result shows that inhibiting effect (CH of the compound to complement system classical pathway 50 ) it is 0.058-0.130mg/ml, to the inhibiting effect (AP of alternative pathway 50 ) it is 0.080-0.390mg/ml.The compound can be used for preparing anticomplement medicament. |
priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.