http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106588846-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6486 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
| filingDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106588846-B |
| titleOfInvention | A kind of preparation method and application of the multi-functional highly sensitive carboxy-lesterase detection fluorescence probe of double Ratio-types |
| abstract | The present invention relates to a kind of preparation method and applications of the highly sensitive carboxy-lesterase detection fluorescence probe of double Ratio-types (ultraviolet/fluorescence) multi-functional (colorimetric/fluorescence/ultraviolet).First, by 2,4- 4-dihydroxy benzaldehyde, glutaconate diethylester and anhydrous piperidines react in ethanol is made product 1, product 1 reacts to obtain product 2 with acetic anhydride in anhydrous pyridine, product 2 reacts to obtain product 3 in tetrahydrofuran with osmium tetroxide, sodium metaperiodate, and product 3 reacts to obtain product 4 in methyl alcohol with Anhydrous potassium carbonate；Secondly, reacting to obtain product 5 in anhydrous ether by picoline and iodomethane；Again, product 4 and product 5 are dissolved in absolute ethanol, piperidines is added and reacts to obtain product 6；Finally, product 6 is dissolved in acetic anhydride, anhydrous sodium acetate is added to get double Ratio-type multi-functional carboxylic acid esterases and detects fluorescence probe.The qualitative and quantitative analysis of carboxy-lesterase suitable for biological sample detects sensitive, accurate, quick；It can be applied to the related fieldss such as analytical chemistry, life organic analytical chemistry, disease are examined in advance and clinical medicine detects. |
| priorityDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 102.