http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106588813-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-494 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q17-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K8-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61Q11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 |
| filingDate | 2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106588813-B |
| titleOfInvention | A kind of novel thiazole class compound XQH-2-92 of Streptococcus mutans and its application |
| abstract | The invention discloses a kind of novel thiazole class compound that can inhibit streptococcus mutans, which is XQH 2 92, molecular formula C 16 H 17 BrN 6 O 4 S, molecular weight 469.31, Chinese are 1 formamide of N (3 bromophenyl) 4 (2 ((5 nitrothiazole, 2 base) amino) 2 oxoethyls) piperazine.Experiment confirm the compound of the present invention under floating state streptococcus mutans type strain and clinical strains show good bacteriostatic activity and bactericidal activity.Meanwhile 99% or more is reached to the inhibiting rate of streptococcus mutans biomembrane when 2 92 final concentrations of compound XQH reach 4mg/L in culture medium.Compound molecular weight of the present invention is small, structure is relatively easy, bacteriostatic experiment confirmation has the characteristics that strong inhibition capability, fragmentation effect are good, the formation of streptococcus mutans planktonic cells and biomembrane can be significantly inhibited, can be had a extensive future as the pilot compound of pre- anti-caries. |
| priorityDate | 2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.