http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106588742-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 |
| filingDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106588742-B |
| titleOfInvention | Hydrogen bond organic catalyst derived from a kind of pyroglutamic acid and its preparation method and application |
| abstract | The present invention provides hydrogen bond organic catalyst derived from a kind of novel pyroglutamic acid, such hydrogen bond organic catalyst is characterized in that they have a chiral centre, contains a five-membered ring lactam structure.Invention also provides a kind of methods for preparing the hydrogen bond catalyst compounds, are simply condensed by pyroglutamic acid and sulfonamide by a step and prepare corresponding hydrogen bond organic catalyst.The preparation method raw material is cheap and easy to get, and synthetic route is succinct, and catalyst is easily prepared.Such hydrogen bond organic catalyst can form dihydrogen bond with indole ketone substrate, show very high stereoselectivity, can be catalyzed the Asymmetric Diels-Alder Reaction of methylene indole ketone compound efficiently, with high selectivity, high enantioselectivity synthesis of indole ketone spiro-compound (>20:1dr, 90%ee). |
| priorityDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 122.