http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106581006-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 |
| filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106581006-B |
| titleOfInvention | Application of the triterpene compound in preparation treatment Parkinson medicinal |
| abstract | The present invention provides a kind of applications of triterpene compound and treatment Parkinson medicinal.The present invention is for blocking be combineding with each other between autophagy skelemin Beclin1 and autophagy inhibiting factor Bcl-2, to induce nerve cell autophagy；And it is used to prepare treatment Parkinson medicinal；The triterpene compound is the mixture of any one of hawthorn acid, tormentic acid or both.It includes pharmaceutically acceptable auxiliary material that the present invention, which treats Parkinson medicinal, further includes the mixture of any one of hawthorn acid, tormentic acid of effective dose or both.Triterpene compound of the present invention, that is, hawthorn acid and tormentic acid can directly block be combineding with each other between autophagy skelemin Beclin1 and autophagy inhibiting factor Bcl-2, to have the function of promoting autophagy in nerve cell.And to the neuroprotection of Parkinson's disease cell.Therefore, hawthorn acid and tormentic acid be can be directly used for into preparation treatment Parkinson medicinal, to assign the good drug effect for the treatment of Parkinson medicinal. |
| priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.