http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106580980-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4402 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
filingDate | 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106580980-B |
titleOfInvention | Application of the aromatic ester compound in preparing anti-enterovirns type 71 drug |
abstract | The invention belongs to antiviral drugs fields.It provides Novel series aromatic ester compound and is preparing anti-enterovirns type 71(EV71)Application in drug.The aromatic ester compound is formula WY59, WY112 compound represented.By Novel series pyridine aromatic ester compound for EV71 inhibitory activity research experiments, WY59, WY112 inhibit the cytopathic effect that EV71 is generated on host cell RD(CPE), enhance cell survival rate, reduce progeny virus production, and can inhibit Apoptosis of Host Cells caused by EV71 infection, mainly act on duplication multiplicative stages of the EV71 in host cell.Show that these novel aromatic ester type compounds there are the potentiality for preparing anti-EV71 virus drugs, these compound synthesis technologies are simple, economical quickly to be easy to mass produce, and have potential applicability in clinical practice. |
priorityDate | 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 18.