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filingDate 2016-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106580879-B
titleOfInvention Amphiphilic short amylose nano particle of ocentyl succinic and preparation method thereof
abstract The present invention relates to a kind of preparation processes of amphiphilic short amylose nano particle of ocentyl succinic, and steps are as follows: (1) with Pullulanase enzymatic hydrolysis gelatinized starch cream, obtaining short amylose;(2) short amylose water solution is prepared, the octenyl succinic acid anhydride solution for being equivalent to short amylose dry powder weight 25-100% is added after gelatinization, persistently stirs 6-10h, obtains the modified short amylose solution of ocentyl succinic;The short amylose of ocentyl succinic is made to the solution of 1-10mg/mL, stirs 6-10h at 37-40 DEG C, is cooled to room temperature to obtain the short amylose nanoparticles solution of ocentyl succinic.Nano particle diameter of the present invention is strong to the adhesive force of tissue between 5-100nm.Hydrophobic active material can be embedded, charging ratio is high, and it is at low cost, gastrointestinal tract is improved to the transfer efficiency of hydrophobic active, improves its bioavailability.Hydrophobic active is protected, its stability is improved, shelters the release of bad flavor;And effectively reduce the additive amount and toxic side effect of bioactive ingredients.
priorityDate 2016-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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