http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106565764-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0213 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-845 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0805 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-0829 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-08 |
| filingDate | 2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106565764-B |
| titleOfInvention | A kind of method of one pot process alpha-chiral silane compound |
| abstract | This method discloses a kind of method of one pot process alpha-chiral silane compound, and using alkynes as raw material, using silane as silicon source, hydrogen is hydroborating reagent, with CoX 2 - OIP complex compound is catalyst, in the presence of sodium triethylborohydride, at a temperature of -30 DEG C~80 DEG C, chiral silane is made in 30 minutes~10 hours one kettle ways of reaction, compared with the conventional method, this method is suitable for a variety of different types of alkynes, and reaction condition is mild, it is easy to operate, Atom economy 100%.In addition, reaction is not necessarily to the addition of other any toxic transition metal salts, there is biggish practical application value on pharmaceutical synthesis.And functional group's tolerance of reaction is good, regioselectivity is also higher, generally 90:10- > 99:1, and enantioselectivity is well extremely outstanding, and ee value is generally > 80%. |
| priorityDate | 2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.