http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106565739-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106565739-B |
| titleOfInvention | A kind of novel gambogic acid-type derivative and its preparation method and application |
| abstract | The invention belongs to anti-tumor drug preparation technical field, a kind of novel gambogic acid-type derivative and its preparation method and application is disclosed；The derivative of the structure with to gambogicacid C-30 be transformed based on, obtain multiple novel Cs -30 substitution benzonitrile class, miazines, imidazoles ester derivant and amide derivatives.These compounds prove there is anti-tumor activity through Bioexperiment, can be used for preparing anti-tumor drug.Part Gamboges acid derivative is quite or more preferable to the inhibitory effect of lung cancer, liver cancer and breast carcinoma cell strain and natural gambogicacid, and part of compounds water solubility is better than gambogicacid, embodies the application value better than gambogicacid. |
| priorityDate | 2016-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.