http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106565587-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106565587-B |
| titleOfInvention | A kind of AURKB micromolecular inhibitors and its application |
| abstract | The invention discloses a kind of AURKB micromolecular inhibitors and its applications.It, which has, effectively kinds of tumor cells to be inhibited to be proliferated, and induces the function of its autophagy.AURKB micromolecular inhibitors provided by the invention are low to normal cell toxicity, and there is significantly expression inhibiting effect to the AURKB H3S10ph modifications mediated and its downstream target gene E2F2, therefore kinds of tumor cells proliferation, Induces Autophagy can effectively be inhibited, to be expected to be developed into new antitumor drug.There is the therapeutic effect of inside and outside to kinds of tumors such as lung cancer, colorectal cancer, breast cancer, acute and chronic leukemias. |
| priorityDate | 2016-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.