Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5170d8ebd19205d193a188716b7155a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abe1e11ef244362285ee5f1dbc7a82a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd01f3ae9850618a63cb738a69fa3a31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_575adee0a6eaa8ad31b144a98915d763 |
publicationDate |
2017-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-106565582-A |
titleOfInvention |
Pentasubstituted pyrrole compound and its preparation method |
abstract |
The invention discloses a pentasubstituted pyrrole compound and a preparation method thereof, which comprises the following steps: 1) adding a nitroepoxy compound, an amine compound, and a butyndioic acid diester in a solvent and at a temperature of 70-90°C The reaction is carried out in a closed container; 2), the reaction solution obtained in step 1) is concentrated, and the obtained concentrate is subjected to silica gel column chromatography to obtain a pentasubstituted pyrrole compound. Pentasubstituted pyrrole compounds have antitumor activity. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107573273-A |
priorityDate |
2016-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |