http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106552293-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 |
| filingDate | 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106552293-B |
| titleOfInvention | A kind of preparation method of the gluconic acid modified hydroxyapatite bone cement of high intensity |
| abstract | The present invention relates to a kind of preparation methods of gluconic acid modified hydroxyapatite bone cement of high intensity, it is using the hydroxyapatite being modified through gluconic acid surface as solid phase powder, using the gluconic acid solution of distilled water or low concentration as solidify liquid, the two obtains high-intensitive gluconic acid modified hydroxyapatite bone cement after reconciling.Bone cement preparation method of the present invention is easy to operate, has good biocompatibility and osteoconductive, and compression strength is high, 78MPa is reached as high as, higher than at present using single-phase hydroxyapatite as the bone cement of solid phase pulvis.PH value can be changed by overcoming first generation PMMA bone cement solidification process thermal discharge height and second generation CPC bone cement solidification process simultaneously, the shortcomings that causing tissue inflammation, solidification process of the present invention is since it is not against acid-base reaction, make around pH value be in neutrality, and heat release is extremely low, and excellent comprehensive performance meets clinical requirement.The present invention is to improve hydroxyapatite bone cement performance to open up new way, widens the application range of gluconic acid. |
| priorityDate | 2016-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.