http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106551939-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106551939-B |
| titleOfInvention | Compound for promoting herpes simplex virus replication and application |
| abstract | The invention belongs to the technical field of biological pharmacy, and relates to a compound for promoting herpes simplex virus replication and application thereof. The present inventors have found that 9 known compounds are capable of promoting the HSV replication process, including JQ-1(PubChem CID 46907787), PFI-1(PubChem CID 71271629), I-BET-762(PubChem CID 46943432), TG101348(PubChem CID 16722836), Quisinostat (PubChem CID 11538455), CUDC-907(PubChem CID 54575456), CUDC-101(PubChem CID 24756910), Givinostat (PubChem CID 9804992), HDAC-42(PubChem CID 6918848). These compounds increase viral infection to varying degrees and can be classified as deacetylase inhibitors (HDACi) or BET bromodomain proteins, such as BRD4 protein (Genbank access NP _490597) bromodomain (bromodomain proteins) inhibitors. They are drugs with the ability of killing tumor alone, and can also be used in tumor treatment and research in combination with HSV. |
| priorityDate | 2016-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.