http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106546465-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-28 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-531 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-28 |
filingDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106546465-B |
titleOfInvention | A kind of breaking method of oil-adjuvant vaccine |
abstract | The present invention provides a kind of breaking methods of oil-adjuvant vaccine, comprising the following steps: mixes oil-adjuvant vaccine with n-butanol, competitor is then added, after oscillation mixes, be centrifuged to get water phase antigen samples;The competitor is at least one of amino acid and its derivative.This method competes antigen binding site and compared with competitor is not added, substantially increases the rate of recovery of antigen in water phase, the rate of recovery reaches 85% or more to discharging the antigen in oil-adjuvant vaccine into water phase by the way that competitor and surfactant is added.And this method can be demulsified to all oil-adjuvant vaccines, while demulsification efficiency is maximized on the basis of original breaking method. |
priorityDate | 2016-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.