http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106543080-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-48 |
| filingDate | 2016-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106543080-B |
| titleOfInvention | A kind of synthetic method of 4- oxos -7- methoxyl groups -1,4- dihydroquinoline -6- methyl formates |
| abstract | The present invention relates to a kind of synthetic methods of 4- oxos -7- methoxyl groups-Isosorbide-5-Nitrae-dihydroquinoline -6- methyl formates, and using 4- nitros-O-Anisic Acid methyl esters as starting material, by Friedel-Crafts reaction, reduction, ammonolysis cyclization obtains target compound.The method of the present invention avoids existing universal method in 180-220 DEG C of decarboxylation ring-forming sequence of diphenyl ether high temperature using classical reaction, solves problem in production, safety and environmental protection is conducive to amplification production.And the method for the present invention has many advantages, such as that reaction efficiency height, high income, purity are high, it is at low cost. |
| priorityDate | 2016-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.