http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106520820-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-75 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-62 |
| filingDate | 2016-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106520820-B |
| titleOfInvention | A method of plasma pro-brain natriuretic peptide levels epitope is prepared using bacillus brevis |
| abstract | A kind of method for preparing plasma pro-brain natriuretic peptide levels epitope using bacillus brevis (Bacillus brevis, B.brevis) of disclosure of the invention.This method will be with the plasma pro-brain natriuretic peptide levels N-terminal linear epitope (NT-BNP in conjunction with plasma pro-brain natriuretic peptide levels antibody 12‑21 ) nucleotides sequence column permutation people fibronectin (fibronectin 3, Fn3) coding the area FG nucleotide sequence, constitute Fn3 and NT-BNP 12‑21 Linear epitope fusion is inserted into shuttle plasmid pNCMO 2 P2 signal peptide downstream, construct pNCMO 2 ‑Fn3‑NT‑BNP 12‑21 Recombinant plasmid, so that recombinant plasmid skelemin Fn3 of energy high efficient expression secreting type in B.brevis merges NT-BNP 12‑21 The fusion protein of linear epitope.The present invention can prepare simple, quickly, efficiently at low cost secreting type have and the comparable fusion protein of plasma pro-brain natriuretic peptide levels antigenicity. |
| priorityDate | 2016-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.