http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106520715-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-26
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-26
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filingDate 2016-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-106520715-B
titleOfInvention A kind of short-chain dehydrogenase and its gene, recombinant expression carrier, genetic engineering bacterium and its application in the synthesis of astaxanthin chiral intermediate
abstract The present invention provides a kind of short-chain dehydrogenase, and its gene, recombinate short-chain dehydrogenase, recombinant expression carrier containing the gene, and genetic engineering bacterium, the preparation method of the recombinase and the short-chain dehydrogenase or application of the genetic engineering bacterium in asymmetric reduction prochiral ketone synthesizing astaxanthin chiral intermediate containing the enzyme.Heretofore described short-chain dehydrogenase asymmetric reduction prepares chiral alcohol with remarkable advantage, can synthesize high-optical-purity astaxanthin chiral intermediate (ee > 99%).Catalyst is easily prepared, reaction condition is mild, substrate wide adaptability, environmental-friendly, and its recombinant cell can in not outer plus any coenzyme system containing isopropanol reaction efficient catalytic prochiral ketone asymmetric reduction, there is good industrial applications development prospect.
priorityDate 2016-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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