http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106520714-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 |
| filingDate | 2015-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106520714-B |
| titleOfInvention | Enzyme process prepares the technique and Alcohol dehydrogenase mutant of chiral 3-hydroxy tetrahydrofuran |
| abstract | The technique of chiral 3-hydroxy tetrahydrofuran is prepared the present invention relates to enzyme process and alcohol takes off enzyme mutant, the following steps are included: the substrate occurs biocatalytic reaction in Alcohol dehydrogenase mutant, co-factor and cofactor regeneration system in buffer system and generates chiral 3-hydroxy tetrahydrofuran using 3- ketone group tetrahydrofuran as substrate；Alcohol dehydrogenase used by the Alcohol dehydrogenase mutant, wild gene sequence derive from Thermophilic Bacteria, base sequence such as SEQ ID No:1；The amino acid sequence of the alcohol dehydrogenase such as SEQ ID No:2.The advantages that enzyme process of the present invention prepares the technique of chiral 3-hydroxy tetrahydrofuran, the technique that chiral 3-hydroxy tetrahydrofuran is prepared using Alcohol dehydrogenase mutant, compared with chemical method, has environmental pollution small, high-efficient, and optical selective is high；Purity with higher and conversion ratio, ee value and conversion ratio can reach 99% compared with enzyme Split Method. |
| priorityDate | 2015-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 508.