http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106512088-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2300-42 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 |
filingDate | 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106512088-B |
titleOfInvention | Phosphatide-glycosaminoglycan bionic extracellular matrix nanometer film and the preparation method and application thereof |
abstract | The present invention relates to a kind of phosphatide-glycosaminoglycan bionic extracellular matrix nanometer films and the preparation method and application thereof, preparation method includes: that glycosaminoglycan is dissolved in phosphate buffer solution, 1- (3- dimethylamino-propyl) -3- ethyl carbodiimide and additive is added, oxygen post activation is removed, additive is 1- hydroxy benzo triazole or N- hydroxysuccinimide;Phosphatide is added in obtained product to be reacted with the mixture of compound emulsion;Obtained product is dry, obtain bionic extracellular matrix nanometer film.Phosphatide provided by the invention-glycosaminoglycan bionic extracellular matrix nanometer film can improve the biocompatibility of bionic extracellular matrix nanometer film while simulating extracellular environment;Make it in Islets cell mass, improves the activity of islet cells, the function of enhancing islet cells release insulin;And the bionic extracellular matrix nanometer membrane preparation method is simple, and reaction condition is mild, easy to operate. |
priorityDate | 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 166.