http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106497996-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-10 |
| filingDate | 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106497996-B |
| titleOfInvention | Enzymatic preparation method of chiral alcohol |
| abstract | The invention discloses an enzyme catalysis preparation method of chiral alcohol, which comprises the following steps: the prochiral ketone compound is mixed with the ketoreductase and the coenzyme provided by the invention, and the pH and the temperature of a system are controlled to carry out reduction reaction. The ketoreductase provided by the invention is used for preparing chiral alcohol by asymmetric reduction of prochiral ketone compounds, has high conversion rate and stereoselectivity, the purity of the product is higher than 95.0%, and the ee value can be higher than 99%. The enzymatic preparation method of chiral alcohol provided by the invention has the advantages of simple reaction steps, shortened production period and saved production cost; the reaction condition is mild, the yield is high, the process condition is stable, the reaction is safe, the operation is simple, and the method has the capability of large-scale production; is environment-friendly, and reduces the pollution of organic solvent to the environment. |
| priorityDate | 2016-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 269.