http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106496247-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_324efbd59cda6faf7813ccb0626896ec |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
filingDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b3ab5d7e0888449a1ea5f49f8cd627a |
publicationDate | 2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106496247-A |
titleOfInvention | A kind of preparation method of ticagrelor intermediate |
abstract | The invention belongs to the technical field of pharmaceutical synthesis, and relates to a method for preparing a ticagrelor intermediate, wherein the method comprises stirring and reacting the compound represented by formula I with titanium tetrachloride under the catalysis of cuprous chloride to obtain ticagrelor Gray Intermediate X, Wherein, G is benzyl or substituted benzyl. Compared with conventional 1-chloroethyl chloroformate or P/C hydrogenation reduction, the method has a huge improvement in the yield of the compound shown in formula X, and has no effect on other groups. |
priorityDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.