| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a9f522cbad67edefa0a5b632915e7ad |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-451
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 |
| filingDate |
2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_131eea0ff0e74ec6c4657b077705bea1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3023a851e23e044f703234a14118345
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a4aafe65f860f77e0966249f117cae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b82b12822c0d6132c6198af4e86a2251 |
| publicationDate |
2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-106496100-A |
| titleOfInvention |
Cyclohexene compounds and their uses |
| abstract |
The invention discloses a cyclohexene compound and its application, belonging to the field of medicinal chemistry. The cyclohexene compound is a cyclohexene compound having the structural characteristics of formula I or a pharmaceutically acceptable salt thereof and an ester-based prodrug or a stereoisomer, and the cyclohexene compound is passed through the influenza virus neuraminic acid Enzyme activity assays have confirmed that they have good inhibitory activity against wild-type and drug-resistant mutant influenza viruses, and the inhibitory activity IC of some compounds on wild-type and drug-resistant mutant influenza virus neuraminidase is less than 5nM, which has significant The effect of inhibiting influenza virus shows that the cyclohexene compound or its pharmaceutically acceptable salt or stereoisomer has superior application prospects in the preparation of anti-influenza virus drugs, thereby providing a new drug option for clinical treatment of influenza . |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018045950-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10919856-B2 |
| priorityDate |
2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |