http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106492190-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-998 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-079 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| filingDate | 2016-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106492190-B |
| titleOfInvention | Method for inducing and maintaining selective polarization of microglia by Hpx protein and application thereof |
| abstract | The invention belongs to the fields of genetic engineering and medicine, and particularly relates to a method for specifically inducing selective polarization of microglia by using a Hemopexin protein and application of the Hemopexin protein in treating spinal cord injury repair. The main technical scheme of the invention is as follows: transplanting microglia into spinal cord of Hemopexin knockout mice to block the microglia from selectively polarizing. And (II) incubating the Hemopexin protein and the microglia can induce and maintain the selective polarization of the microglia. Hemopexin induces microglia to present an M2 phenotype, and can effectively promote the repair of spinal nerve injury. |
| priorityDate | 2016-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 383.