http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478780-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-16 |
| filingDate | 2017-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106478780-B |
| titleOfInvention | Preparation method of oxytocin [4-Glu ] |
| abstract | The invention discloses a preparation method of oxytocin [4-Glu ]. The preparation method comprises the following steps: performing reverse phase cyclization, reverse phase purification and reverse phase desalting on the oxytocin [4-Glu ] precursor crude product solution by adopting a high performance liquid reverse phase chromatography in sequence; the filler of the high performance liquid reverse phase chromatography is silica gel C18; the oxytocin [4-Glu ] precursor crude product is an oxytocin [4-Glu ] precursor crude product containing two free sulfydryl groups. The invention innovatively applies the cyclization, purification and desalination by a reversed-phase adsorption method, solves the problems of cyclization, purification and desalination at one time, optimizes the production process and is suitable for industrial continuous production. |
| priorityDate | 2017-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.