http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478689-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F1-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F1-08 |
filingDate | 2016-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106478689-B |
titleOfInvention | The chlorination copper complex of 1- (2- pyridines) -9- (4- methyl-benzyls)-B-carboline and its synthetic method and application |
abstract | Chlorination copper complex and its synthetic method and application the invention discloses a kind of 1 (2 pyridine) 9 (4 methyl-benzyl) β carbolines.Shown in the structural formula of the complex such as following formula (I), its synthetic method is:Take compound and copper chloride as shown in following formula (II), be dissolved in polar solvent, carry out complexation reaction, to obtain the final product;Wherein, the polar solvent is selected from one or both of methanol and ethanol and the combination more than one or both of water, acetone, chloroform, dichloromethane and N, N dimethylformamide.Complex of the present invention is shown than ligand and the stronger antitumor activity of cis-platinum, is had preferable potential medical value, is expected to be used for the preparation of various antitumor drugs.Structure shown in formula (I) and formula (II) is as follows: |
priorityDate | 2016-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.