http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478653-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2016-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-106478653-B |
| titleOfInvention | Mono- imidazole salt compound of isobide-and preparation method thereof |
| abstract | There is general structure the invention discloses a series of（Such as figure I or II）The mono- imidazole salt compound of isobide-and preparation method thereof, using isobide as raw material, isobide methanesulfonates is converted under the conditions of anhydrous pyridine with mesyl chloride, then with 2 methylimidazoles or 5,6 dimethylbenzimidazoles heat the reaction synthesis mono- imidazoles of isobide-in anhydrous DMF solvent, and back flow reaction has synthesized the mono- imidazole salt compound of isobide-in toluene solvant with brominated alkanes on this basis.Such compound shows preferable analgesic activity. |
| priorityDate | 2016-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.